Hmmer

Jul 20, 2023

Profile hidden Markov models for biological sequence analysis

HMMER is an implementation of profile hidden Markov model methods for sensitive searches of biological sequence databases using multiple sequence alignments as queries.

Given a multiple sequence alignment as input, HMMER builds a statistical model called a “hidden Markov model” which can then be used as a query into a sequence database to find and/or align additional homologues of the sequence family.



Checkout these related ports:
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  • Viennarna - Alignment tools for the structural analysis of RNA
  • Velvet - Sequence assembler for very short reads
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  • Vcflib - C++ library and CLI tools for parsing and manipulating VCF files
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  • Ugene - Integrated bioinformatics toolkit
  • Ucsc-userapps - Command line tools from the UCSC Genome Browser project
  • Trimmomatic - Flexible read trimming tool for Illumina NGS data