May 26, 2018
Bayesian inference of phylogeny
MrBayes is a program for the Bayesian estimation of phylogeny.
Bayesian inference of phylogeny is based upon a quantity called the posterior probability distribution of trees, which is the probability of a tree conditioned on the observations. The conditioning is accomplished using Bayes’s theorem. The posterior probability distribution of trees is impossible to calculate analytically; instead, MrBayes uses a simulation technique called Markov chain Monte Carlo or MCMC to approximate the posterior probabilities of trees.